Global approach to systems biology: This presentation was given at the University of California’s Center for Integrative Medicine’s Journal club in June of 2013. It is a summary of the landmark article “Endobiogeny: A global approach to systems biology, parts 1 and 2.” It develops in detail, the concepts of systems biology, the biomarkers used in the biology of functions and their relationship to neuro-endocrine function. The audio recording of the presentation is included for greater clarity and comprehension.